Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28376947 | 0.80 | SLC9A1 (0.48) | ALDH1A1SLC9A1LMNATP53KDM4E | |
| SCHEMBL28380943 | 0.80 | SLC9A1 (0.48) | ALDH1A1SLC9A1LMNATP53KDM4E | |
| SCHEMBL31406306 | 0.79 | SLC9A1 (0.59) | ALDH1A1SLC9A1LMNATP53KDM4E | |
| SCHEMBL22492109 | 0.77 | AKR1C3 (0.46) | ALDH1A1LMNAGAATSHRL3MBTL1 | |
| SCHEMBL22492107 | 0.77 | AKR1C3 (0.46) | ALDH1A1LMNAGAATSHRL3MBTL1 | |
| SCHEMBL7002979 | 0.77 | SLC9A1 (0.67) | ALDH1A1SLC9A1LMNATP53KDM4E | |
| SCHEMBL5775091 | 0.77 | SLC9A1 (0.67) | ALDH1A1SLC9A1LMNATP53KDM4E | |
| SCHEMBL6902353 | 0.77 | SLC9A1 (0.67) | ALDH1A1SLC9A1LMNATP53KDM4E | |
| SCHEMBL25350693 | 0.77 | LMNA (0.46) | ALDH1A1SLC9A1LMNAKDM4EGAA | |
| SCHEMBL10843264 | 0.76 | TP53 (0.50) | ALDH1A1SLC9A1LMNATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151640-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |