Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406451 | 0.78 | LMNA (0.49) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL25346259 | 0.77 | ALDH1A1 (0.46) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL4169410 | 0.74 | ALDH1A1 (0.58) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL28376947 | 0.73 | SLC9A1 (0.48) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL28380943 | 0.73 | SLC9A1 (0.48) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL16824940 | 0.72 | LMNA (0.55) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL177270 | 0.72 | LMNA (0.55) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL177269 | 0.72 | LMNA (0.55) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL30317990 | 0.72 | TSHR (0.59) | LMNATDP1TSHRALDH1A1KDM4E | |
| SCHEMBL10046438 | 0.72 | TSHR (0.59) | LMNATDP1TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151640-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |