SCHEMBL25346540

SCHEMBL25346540

O=C(O)CCC(=O)OC(=O)c1cccnc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
APP P05067 1/20 0.51
GAA P10253 1/20 0.51
HCAR3 P49019 1/20 0.51
HCAR2 Q8TDS4 1/20 0.51
TBXAS1 P24557 13/20 0.51
L3MBTL1 Q9Y468 1/20 0.49
PLOD2 O00469 1/20 0.49
TBXA2R P21731 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28994933 0.91 TBXAS1 (0.55) ALDH1A1LMNAKMT2ATDP1TBXAS1
SCHEMBL17895063 0.86 ALDH1A1 (0.66) ALDH1A1LMNAKMT2ATDP1TBXAS1
SCHEMBL9696292 0.86 ALDH1A1 (0.60) ALDH1A1LMNAKMT2ATDP1APP
SCHEMBL27623813 0.86 ALDH1A1 (0.56) ALDH1A1LMNAKMT2ATDP1APP
SCHEMBL6762577 0.85 ALDH1A1 (0.51) ALDH1A1LMNAKMT2ATDP1APP
SCHEMBL4646985 0.84 ALDH1A1 (0.54) ALDH1A1LMNAKMT2ATDP1APP
SCHEMBL23069546 0.84 L3MBTL1 (0.60) ALDH1A1LMNAKMT2ATDP1APP
SCHEMBL9696285 0.83 ALDH1A1 (0.66) ALDH1A1LMNAKMT2ATDP1APP
SCHEMBL4996696 0.82 ALDH1A1 (0.64) ALDH1A1LMNAKMT2ATDP1APP
SCHEMBL514512 0.82 ALDH1A1 (0.59) ALDH1A1LMNAKMT2ATDP1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912691-B2 Tocotrienols derivates, methods and uses thereof GLOBAL SCIENTIFIC (US) 2024-02-27 US disclosed
US-20230271948-A1 TOCOTRIENOLS DERIVATES, METHODS AND USES THEREOF GLOBAL SCIENTIFIC (US) 2023-08-31 US disclosed
EP-4225299-A1 TOCOTRIENOLS DERIVATES, METHODS AND USES THEREOF Global Scientific (US) 2023-08-16 EP disclosed
CN-116390713-A Tocotrienol derivatives, methods and uses thereof 全球科学公司 2023-07-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912691-B2 Tocotrienols derivates, methods and uses thereof NAMPT, NAPRT, NNT ALDH1A1 849/4885LMNA 891/4885KMT2A 3297/4885
US-20230271948-A1 TOCOTRIENOLS DERIVATES, METHODS AND USES THEREOF NAMPT, NAPRT, NNT ALDH1A1 849/4885LMNA 891/4885KMT2A 3297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.