Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.75 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.75 |
| ▸ | APP | P05067 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.71 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA3 | P07451 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.66 |
| ▸ | CA6 | P23280 | 1/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945375 | 1.00 | NFE2L2 (0.75) | NFE2L2TUBB1APPMAPTTTR | |
| SCHEMBL4938984 | 1.00 | NFE2L2 (0.75) | NFE2L2TUBB1APPMAPTTTR | |
| Isoeugenol SCHEMBL2686818 | 0.92 | TYR (0.84) | NFE2L2TUBB1APPMAPTTTR | |
| Cis/Trans-Isoeugenol SCHEMBL2686822 | 0.92 | TYR (0.84) | NFE2L2TUBB1APPMAPTTTR | |
| SCHEMBL17732299 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL671150 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL30807100 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL671149 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL5598747 | 0.88 | CYP2D6 (0.85) | NFE2L2APPMAPTCYP1A2TYR | |
| Ferulate SCHEMBL28581353 | 0.88 | KDM4E (0.88) | NFE2L2APPMAPTCYP1A2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801087-B1 | CIS-1,2-SUBSTITUTED STILBENE DERIVATIVES FOR TREATING AND/OR PREVENTING DIABETES | INST RADIATION MED AMMS PLA (CN) | 2012-08-29 | — | — | EP | disclosed |
| US-8039513-B2 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2011-10-18 | — | — | US | disclosed |
| US-8039513-B2 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2011-10-18 | — | — | US | disclosed |
| US-8039513-B2 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2011-10-18 | — | — | US | disclosed |
| US-20090161561-A1 | Method and system for determining characters of channels | HUAWEI TECHNOLOGIES CO., LTD | 2009-06-25 | — | — | US | disclosed |
| US-20090161561-A1 | Method and system for determining characters of channels | HUAWEI TECHNOLOGIES CO., LTD | 2009-06-25 | — | — | US | disclosed |
| US-20090161561-A1 | Method and system for determining characters of channels | HUAWEI TECHNOLOGIES CO., LTD | 2009-06-25 | — | — | US | disclosed |
| US-20090076114-A1 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2009-03-19 | — | — | US | disclosed |
| US-20090076114-A1 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2009-03-19 | — | — | US | disclosed |
| US-20090076114-A1 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2009-03-19 | — | — | US | disclosed |
| EP-1801087-A1 | CIS-1,2-SUBSTITUTED STILBENE DERIVATES AND THE USE THEREROF FOR MANUFACTURING MEDICAMENTS FOR TREATING MEDICAMENTS FOR TREATING AND/OR PREVENTING DIABETES | Institute of Radiation Medicine, Academy of Military Medical Sciences Pla (CN) | 2007-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076114-A1 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | SLC5A1, SLC5A2, SLC2A1 | NFE2L2 285/4885TUBB1 1508/4885APP 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.