Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.75 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.75 |
| ▸ | APP | P05067 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.71 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA3 | P07451 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.66 |
| ▸ | CA6 | P23280 | 1/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534835 | 1.00 | NFE2L2 (0.75) | NFE2L2TUBB1APPMAPTTTR | |
| SCHEMBL4938984 | 1.00 | NFE2L2 (0.75) | NFE2L2TUBB1APPMAPTTTR | |
| Isoeugenol SCHEMBL2686818 | 0.92 | TYR (0.84) | NFE2L2TUBB1APPMAPTTTR | |
| Cis/Trans-Isoeugenol SCHEMBL2686822 | 0.92 | TYR (0.84) | NFE2L2TUBB1APPMAPTTTR | |
| SCHEMBL17732299 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL671150 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL30807100 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL671149 | 0.91 | TTR (0.85) | NFE2L2APPMAPTTTRCYP1A2 | |
| SCHEMBL5598747 | 0.88 | CYP2D6 (0.85) | NFE2L2APPMAPTCYP1A2TYR | |
| Ferulate SCHEMBL28581353 | 0.88 | KDM4E (0.88) | NFE2L2APPMAPTCYP1A2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139650-A1 | Fungicidally Active Polymer Dispersions And Use Thereof | CELANESE EMULSIONS GMBH (DE) | 2008-06-12 | — | — | US | claimed |
| CN-110187119-B | Methods and compositions for the detection and treatment of preeclampsia | 耶鲁大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-110187121-B | Methods and compositions for the detection and treatment of preeclampsia | 耶鲁大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110187120-B | Methods and compositions for the detection and treatment of preeclampsia | 耶鲁大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-111936628-A | Alzheimer disease animal model and application thereof | 清华大学 | 2020-11-13 | — | — | CN | disclosed |
| US-9925153-B2 | Therapeutic agents for skin diseases and conditions | STC.UNM (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM | 2016-10-06 | — | — | US | disclosed |
| US-8980954-B2 | Substituted cis- and trans-stilbenes as therapeutic agents | STC.UNM (US) | 2015-03-17 | — | — | US | disclosed |
| US-8716532-B2 | One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-05-06 | — | — | US | disclosed |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | STC.UNM (US) | 2013-07-11 | — | — | US | disclosed |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-28 | — | — | US | disclosed |
| WO-2010113005-A2 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-10-07 | — | — | WO | disclosed |
| US-7759527-B2 | Microwave induced one pot process for the preparation of arylethenes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20080139650-A1 | Fungicidally Active Polymer Dispersions And Use Thereof | CELANESE EMULSIONS GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080045752-A1 | Microwave Induced One Pot Process For The Preparation Of Arylethenes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-21 | — | — | US | disclosed |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2007-10-25 | — | — | US | disclosed |
| WO-2007110881-A1 | A MICROWAVE INDUCED ONE POT PROCESS FOR THE PREPARATION OF ARYLETHENES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-10-04 | — | — | WO | disclosed |
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045752-A1 | Microwave Induced One Pot Process For The Preparation Of Arylethenes | TET2, HCN4, KDM4E | NFE2L2 732/4885TUBB1 1384/4885APP 3839/4885 |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | CUTA, TSLP, ELANE | NFE2L2 696/4885TUBB1 15/4885APP 475/4885 |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | SIK1, SIK2, HCK | NFE2L2 237/4885TUBB1 374/4885APP 2941/4885 |
| US-20080139650-A1 | Fungicidally Active Polymer Dispersions And Use Thereof | CBR3, CBR1, CYP3A4 | NFE2L2 3306/4885TUBB1 348/4885APP 3335/4885 |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | TGFB1, VHL, TMSB10 | NFE2L2 68/4885TUBB1 33/4885APP 546/4885 |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | PSEN1, TERT, PSEN2 | NFE2L2 63/4885TUBB1 120/4885APP 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.