Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 4/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30545684 | 1.00 | PRMT1 (0.50) | PRMT1FOLH1PTPN1PRMT5CARM1 | |
| Bromide SCHEMBL25348580 | 0.89 | PRMT1 (0.48) | PRMT1FOLH1PTPN1PRMT5CARM1 | |
| Bromide SCHEMBL25348571 | 0.89 | PRMT1 (0.48) | PRMT1FOLH1PTPN1PRMT5CARM1 | |
| Bromide SCHEMBL30545636 | 0.88 | PRMT1 (0.47) | PRMT1FOLH1PTPN1PRMT5CARM1 | |
| Bromide SCHEMBL25349033 | 0.88 | PRMT1 (0.47) | PRMT1FOLH1PTPN1PRMT5CARM1 | |
| Bromide SCHEMBL31555980 | 0.86 | PRMT1 (0.42) | PRMT1FOLH1 | |
| Bromide SCHEMBL30545611 | 0.84 | FOLH1 (0.41) | PRMT1FOLH1 | |
| Bromide SCHEMBL25349036 | 0.81 | PRMT1 (0.46) | PRMT1FOLH1PTPN1PRMT5CARM1 | |
| Bromide SCHEMBL25349028 | 0.81 | PRMT1 (0.46) | PRMT1FOLH1PTPN1PRMT5CARM1 | |
| SCHEMBL25349596 | 0.81 | LMNA (0.42) | PRMT1FOLH1PTPN1PRMT5CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154762-A1 | SQUARAINE FLUOROPHORES | THE GENERAL HOSPITAL CORPORATION (US) | 2023-08-17 | — | — | WO | disclosed |