SCHEMBL25348593

SCHEMBL25348593

[c]1ccc2c(c1)C(C1c3ccccc3-c3ccccc31)c1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.35
HTR2A P28223 1/20 0.35
CYP1A2 P05177 2/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3873041 0.79 GPR3 (0.38) GPR3HTR2APOLBMEN1KMT2A
SCHEMBL9620670 0.79 KDM4E (0.39) GPR3HTR2APOLBMEN1KMT2A
SCHEMBL524603 0.78 GPR3 (0.50) GPR3HTR2ACYP1A2MAPK1POLB
SCHEMBL29950614 0.78 GPR3 (0.50) GPR3HTR2ACYP1A2MAPK1POLB
SCHEMBL3093711 0.76 LMNA (0.39) GPR3HTR2ACYP1A2MAPK1POLB
SCHEMBL28543582 0.75 CA1 (0.31) GPR3HTR2APOLBHDAC3HDAC4
SCHEMBL3871024 0.75 HTR2A (0.42) GPR3HTR2APOLBMEN1KMT2A
SCHEMBL29196034 0.75 PTGS2 (0.39) GPR3HTR2ACYP1A2CYP2D6
SCHEMBL2763555 0.72 ATM (0.46) HTR2APOLBKMT2AATMHDAC3
SCHEMBL27969025 0.72 HTR2A (0.40) GPR3HTR2ACYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255111-A1 ORGANIC LIGHT-EMITTING DIODE EUROPIUM CORPORATION (JP) 2023-08-10 US disclosed