Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 8/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4415432 | 0.98 | CYP1A2 (0.52) | CYP1A2ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL31126988 | 0.90 | EPHX1 (0.55) | CYP1A2ACHECYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL27673522 | 0.88 | ACHE (0.64) | ACHESMN1; SMN2EPHX2 | |
| SCHEMBL1425763 | 0.88 | GAA (0.52) | CYP1A2ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL10778878 | 0.86 | ACHE (0.53) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7570219 | 0.85 | ACHE (0.61) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21068069 | 0.85 | ACHE (0.61) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL50331 | 0.84 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19ALDH1A1GAA | |
| SCHEMBL7385877 | 0.84 | ACHE (0.52) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7770088 | 0.84 | ACHE (0.52) | ACHEHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110386882-A | (S) preparation method of the chloro- 2- of -4- ((ethoxy carbonyl) amino) ethyl butyrate | 利尔化学股份有限公司 | 2019-10-29 | — | — | CN | claimed |
| US-20230257740-A1 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETIN | BANK OF AMERICA, N.A. | 2023-08-17 | — | — | US | disclosed |
| CN-110386882-A | (S) preparation method of the chloro- 2- of -4- ((ethoxy carbonyl) amino) ethyl butyrate | 利尔化学股份有限公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110386882-A | (S) preparation method of the chloro- 2- of -4- ((ethoxy carbonyl) amino) ethyl butyrate | 利尔化学股份有限公司 | 2019-10-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257740-A1 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETIN | TTR, RNGTT, RNASE1 | CYP1A2 4540/4885ACHE 3277/4885HDAC3 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.