Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL10332764 | 1.00 | TDP1 (0.34) | TDP1PTGS1AKR1C3MAPTL3MBTL1 | |
| SCHEMBL214693 | 0.95 | — | — | |
| SCHEMBL272875 | 0.95 | — | — | |
| Methacrylic Acid SCHEMBL27367883 | 0.85 | TDP1 (0.32) | TDP1PTGS1AKR1C3 | |
| Propionamide SCHEMBL27774233 | 0.80 | FFAR3 (0.31) | TDP1ALDH1A1FFAR3 | |
| SCHEMBL28067686 | 0.76 | — | — | |
| SCHEMBL15930121 | 0.75 | — | — | |
| SCHEMBL10473160 | 0.75 | — | — | |
| SCHEMBL9720653 | 0.75 | — | — | |
| SCHEMBL28619119 | 0.72 | PTGS1 (0.36) | PTGS1AKR1C3FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110256510-A1 | Use of Quaternary Ammonium Compounds to Inhibit Endogenous MMPs in Tooth Dentin | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-10-20 | — | — | US | claimed |
| WO-2010081104-A1 | USE OF POLYMERI ZABLE QUATERNARY AMMONIUM COMPOUNDS TO INHIBIT ENDOGENOUS MMPS IN TOOTH DENTIN | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| JP-2038615-A | — | — | None | — | — | JP | disclosed |
| US-20110256510-A1 | Use of Quaternary Ammonium Compounds to Inhibit Endogenous MMPs in Tooth Dentin | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-10-20 | — | — | US | disclosed |
| WO-2010081104-A1 | USE OF POLYMERI ZABLE QUATERNARY AMMONIUM COMPOUNDS TO INHIBIT ENDOGENOUS MMPS IN TOOTH DENTIN | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| JP-H0238615-A | METHOD FOR IMPROVING QUALITY OF MOIST SURPLUS SOIL | KURITA WATER IND LTD | 1990-02-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256510-A1 | Use of Quaternary Ammonium Compounds to Inhibit Endogenous MMPs in Tooth Dentin | MMP1, MMP2, MMP7 | TDP1 963/4885PTGS1 428/4885AKR1C3 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.