Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 6/20 | 0.41 |
| ▸ | PYGL | P06737 | 3/20 | 0.41 |
| ▸ | PYGM | P11217 | 2/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954873 | 1.00 | PYGB (0.41) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL3707213 | 0.87 | LGALS1 (0.35) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL3711213 | 0.87 | PYGB (0.38) | PYGBPYGLPYGMCDK1CCNB1 | |
| SCHEMBL3963865 | 0.77 | MEN1 (0.41) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL31310161 | 0.77 | MEN1 (0.41) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL31175314 | 0.77 | MEN1 (0.41) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL2216585 | 0.77 | MEN1 (0.41) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL3459153 | 0.77 | MEN1 (0.41) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL2218756 | 0.77 | MEN1 (0.41) | PYGBPYGLPYGMLGALS1LGALS3 | |
| SCHEMBL851105 | 0.74 | LGALS1 (0.44) | PYGBLGALS1LGALS3LGALS9LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044182-B2 | Adiponectin and uses thereof | PHILERA NEW ZEALAND LIMITED (NZ) | 2011-10-25 | — | — | US | disclosed |
| US-20100016216-A1 | Adiponectin and uses thereof | PHILERA NEW ZEALAND LIMITED (NZ) | 2010-01-21 | — | — | US | disclosed |
| US-7365170-B2 | Reagents for regulation of metabolic events, such as those mediated by adiponectin and adiponectin agonists. The invention also provides screening assays for identification of biologically active agents, diagnostic and therapeutic agents | PROTEMIX CORPORATION (NZ) | 2008-04-29 | — | — | US | disclosed |
| EP-1474445-A1 | GLYCOISOFORMS OF ADIPONECTIN AND USES THEREOF | Protemix Corporation Limited (NZ) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004056861-A2 | GLYCOISOFORMS OF ADIPONECTIN AND USES THEREOF | PROTEMIX CORPORATION LIMITED (US) | 2004-07-08 | — | — | WO | disclosed |
| US-20040023854-A1 | Adiponectin and uses thereof | PROTEMIX CORPORATION LIMITED (NZ) | 2004-02-05 | — | — | US | disclosed |
| WO-2003062275-A1 | GLYCOISOFORMS OF ADIPONECTIN AND USES THEREOF | PROTEMIX CORPORATION LIMITED (NZ) | 2003-07-31 | — | — | WO | disclosed |