Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.38 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707213 | 0.88 | LGALS1 (0.35) | PYGBPYGLPYGMCDK1CCNB1 | |
| SCHEMBL2535185 | 0.87 | PYGB (0.41) | PYGBPYGLPYGMCDK1CCNB1 | |
| SCHEMBL3954873 | 0.87 | PYGB (0.41) | PYGBPYGLPYGMCDK1CCNB1 | |
| SCHEMBL3711538 | 0.84 | CA2 (0.33) | — | |
| SCHEMBL29932427 | 0.80 | PYGB (0.35) | PYGBPYGLPYGM | |
| SCHEMBL3714856 | 0.71 | PYGB (0.46) | PYGBPYGLPYGMCDK1CCNB1 | |
| SCHEMBL24518019 | 0.70 | LGALS1 (0.52) | PYGB | |
| SCHEMBL13110610 | 0.70 | LGALS1 (0.52) | PYGB | |
| SCHEMBL12252964 | 0.70 | LGALS1 (0.52) | PYGB | |
| SCHEMBL9914006 | 0.70 | LGALS1 (0.52) | PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102673-A1 | HELLEBRIN AND HELLEBRIGENIN DERIVATIVES | UNIBIOSCREEN S.A. (BE) | 2010-09-16 | — | — | WO | claimed |
| WO-2010102673-A1 | HELLEBRIN AND HELLEBRIGENIN DERIVATIVES | UNIBIOSCREEN S.A. (BE) | 2010-09-16 | — | — | WO | disclosed |