⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008509 | 1.00 | LMNA (0.41) | — | |
| SCHEMBL2537647 | 1.00 | LMNA (0.41) | — | |
| SCHEMBL2537558 | 0.97 | — | — | |
| SCHEMBL9496477 | 0.88 | — | — | |
| SCHEMBL9497904 | 0.88 | — | — | |
| SCHEMBL1721677 | 0.88 | — | — | |
| SCHEMBL541455 | 0.85 | TRPV1 (0.36) | — | |
| SCHEMBL7217395 | 0.82 | ALDH1A1 (0.39) | — | |
| SCHEMBL28938914 | 0.79 | LMNA (0.38) | — | |
| Chloroform SCHEMBL8030698 | 0.79 | LMNA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114316102-B | Alkoxy magnesium carrier, polyethylene catalyst and preparation method thereof | 北京吉海川科技发展有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-114316102-A | Alkoxy magnesium carrier, polyethylene catalyst and preparation method thereof | 北京吉海川科技发展有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-8044070-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20100210637-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | MSD K.K. (JP) | 2010-08-19 | — | — | US | disclosed |
| US-7595316-B2 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-29 | — | — | US | disclosed |
| US-20060178375-A1 | Heteroaryloxy nitrogenous saturated heterocyclic derivative | MSD K.K. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1642898-A1 | HETEROARYLOXY NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-04-05 | — | — | EP | disclosed |
| CN-1017902-B | PROCESS FOR THE PREPARATION OF NOVEL CEPHALOSPORIN DERIVATIVES | MEIJI PHARMACEUTIAL LTD (JP) | 1992-08-19 | — | — | CN | disclosed |
| CN-85105120-A | The preparation method of novel cephalosporin derivatives | — | 1986-12-31 | — | — | CN | disclosed |