Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinchlorimide SCHEMBL25354882 | 0.88 | MEN1 (0.39) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL1869874 | 0.85 | CTSL (0.44) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL6469380 | 0.82 | OPRM1 (0.59) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL17103566 | 0.81 | OPRM1 (0.43) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL17103567 | 0.81 | OPRM1 (0.43) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL6108529 | 0.81 | OPRM1 (0.54) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL3827609 | 0.81 | OPRM1 (0.54) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL25360969 | 0.80 | OPRM1 (0.46) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL17803548 | 0.79 | CARM1 (0.52) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL25355327 | 0.79 | CARM1 (0.46) | OPRM1OPRL1DPP4SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |