SCHEMBL25356142

SCHEMBL25356142

O=C(C=NO)Nc1ccc(Cl)cc1Br

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.68
POLB P06746 1/20 0.49
CXCR2 P25025 1/20 0.44
CYP1A2 P05177 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 2/20 0.42
EGFR P00533 1/20 0.40
GRIK1 P39086 1/20 0.40
NPC1 O15118 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
TP53 P04637 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074425 0.84 MAPK1 (0.72) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL3074427 0.84 MAPK1 (0.72) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL23251378 0.81 MAPK1 (1.00) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL25356392 0.81 MAPK1 (1.00) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL20504663 0.79 MAPK1 (0.66) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL20504662 0.79 MAPK1 (0.66) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL25280007 0.79 MAPK1 (0.50) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL30414431 0.79 MAPK1 (0.50) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL25234430 0.79 MAPK1 (0.50) MAPK1POLBCYP1A2NPSR1MEN1
SCHEMBL12529037 0.78 MAPK1 (0.78) MAPK1POLBKMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339906-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2023-10-26 US disclosed
CN-116547266-A Synthesis method of anthranilic acid/amide compound and intermediate thereof 皮埃企业有限公司 2023-08-04 CN disclosed
EP-4217339-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI Industries Ltd. (IN) 2023-08-02 EP disclosed
WO-2022064454-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339906-A1 A PROCESS FOR THE SYNTHESIS OF ANTHRANILIC ACID/AMIDE COMPOUNDS AND INTERMEDIATES THEREOF ASS1, ARG1, NQO2 MAPK1 976/4885POLB 861/4885CXCR2 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.