SCHEMBL25356153

SCHEMBL25356153

CC(C)(C)c1ccc(/C(=C\C=O)c2ccc(Br)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41
HIF1A Q16665 1/20 0.41
SRD5A2 P31213 1/20 0.41
HDAC3 O15379 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
HDAC11 Q96DB2 1/20 0.39
RAB9A P51151 2/20 0.38
MAP3K5 Q99683 1/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
POLB P06746 1/20 0.38
RARB P10826 1/20 0.38
RARG P13631 1/20 0.38
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28031837 0.91 HDAC1 (0.48) HDAC1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL6387039 0.85 CES2 (0.48) HDAC1MEN1KMT2AALDH1A1HDAC3
SCHEMBL13676239 0.79 EPHX2 (0.43) HDAC1MEN1KMT2AALDH1A1HTT
SCHEMBL1320539 0.78 CYP1B1 (0.44) MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A
SCHEMBL20139669 0.78 CYP1B1 (0.44) MEN1KMT2ASMN1; SMN2ALDH1A1RAB9A
SCHEMBL2683558 0.77 ESR1 (0.47) HDAC1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL2683557 0.77 ESR1 (0.47) HDAC1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL28609678 0.77 HDAC1 (0.46) HDAC1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL25317423 0.76 MAPT (0.53) HDAC1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL2685393 0.76 SRD5A2 (0.68) HDAC1MEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022178427-A9 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2023-07-27 WO disclosed