Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818774 | 0.83 | ACHE (0.41) | ACHETSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1007134 | 0.83 | — | — | |
| SCHEMBL11454828 | 0.82 | KDM4E (0.43) | ACHEKDM4E | |
| SCHEMBL8781841 | 0.82 | KDM4E (0.48) | ACHEKDM4E | |
| SCHEMBL4278680 | 0.82 | KDM4E (0.48) | ACHEKDM4E | |
| Bromide SCHEMBL11554860 | 0.81 | — | — | |
| SCHEMBL8521269 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL15512214 | 0.81 | ACHE (0.40) | ACHETSHRALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL29086935 | 0.81 | — | — | |
| SCHEMBL6934467 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122760-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | THOMPSON, PATRICK R. | 2012-05-17 | — | — | US | disclosed |
| US-8034977-B2 | Lipids for transfection of nucleic acids | MOLECULAR TRANSFER, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-20090215067-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | MOLECULAR TRANSFER, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-7531693-B2 | Lipids for transfection of nucleic acids | MOLECULAR TRANSFER, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| EP-1628647-A4 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | MOLECULAR TRANSFER INC (US) | 2007-10-24 | — | — | EP | disclosed |
| EP-1628647-A2 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | Molecular Transfer, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| US-20050014962-A1 | Novel lipids for transfection of nucleic acids | THOMPSON AND PATRICIA A THOMPSON AS TRUSTEES OF THE THOMPSON FAMILY TRUST DATED AUGUST 27 2002, JOHN D. | 2005-01-20 | — | — | US | disclosed |
| WO-2004105697-A2 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | MOLECULAR TRANSFER, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014962-A1 | Novel lipids for transfection of nucleic acids | ABHD16A, MBOAT7, NPC1L1 | ACHE 4881/4885TSHR 3393/4885ALDH1A1 4821/4885 |
| US-20090215067-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | ABHD16A, MBOAT7, NPC1L1 | ACHE 4881/4885TSHR 3393/4885ALDH1A1 4821/4885 |
| US-20120122760-A1 | NOVEL LIPIDS FOR TRANSFECTION OF NUCLEIC ACIDS | ABHD16A, MBOAT7, NPC1L1 | ACHE 4881/4885TSHR 3393/4885ALDH1A1 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.