SCHEMBL4278680

SCHEMBL4278680

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nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
PDE4A P27815 1/20 0.34
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8781841 1.00 KDM4E (0.48) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL11454828 0.96 KDM4E (0.43) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL19114066 0.82 KDM4E (0.35) KDM4EACHE
SCHEMBL17850547 0.82 KDM4E (0.31) KDM4E
SCHEMBL2535752 0.82 ACHE (0.34) KDM4EACHE
SCHEMBL9444652 0.79 LMNA (0.65) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL5551085 0.79 LMNA (0.65) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL29344590 0.79 LMNA (0.65) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL724112 0.79 LMNA (0.65) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL16357689 0.77 KDM4E (0.42) KDM4ELMNAL3MBTL1TDP1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618216-B1 N-alkylisomaltamines, their preparation from isomaltulose and their application as surfactants SUEDZUCKER AG (DE) 1997-09-10 EP claimed
JP-55062004-A None JP disclosed
US-20090042749-A1 N,N-Dialkylpolyhydroxyalkylamines AIR PRODUCTS AND CHEMICALS, INC. (US) 2009-02-12 US disclosed
EP-1676831-B1 N,N-dialkylpolyhydroxyalkylamines AIR PROD & CHEM (US) 2008-10-08 EP disclosed
EP-1676831-A1 N,N-dialkylpolyhydroxyalkylamines Air Products and Chemicals, Inc. (US) 2006-07-05 EP disclosed
US-20060100127-A1 N,N-dialkylpolyhydroxyalkylamines AIR PRODUCTS AND CHEMICALS, INC. 2006-05-11 US disclosed
EP-1637038-A2 N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines AIR PRODUCTS AND CHEMICALS, INC. (US) 2006-03-22 EP disclosed
US-20060013780-A1 N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines AIR PRODUCTS AND CHEMICALS, INC. 2006-01-19 US disclosed
EP-0618216-A1 N-alkylisomaltamines, their preparation from isomaltulose and their application as surfactants SÜDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) 1994-10-05 EP disclosed
JP-S5562004-A CONTROL AGENT AGAINST PLANT VIRAL DISEASE KUREHA CHEM IND CO LTD 1980-05-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060013780-A1 N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines AGL, SFN, MGAT1 KDM4E 3607/4885LMNA 492/4885L3MBTL1 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.