Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690320 | 0.87 | DHODH (0.42) | DHODHAADAT | |
| SCHEMBL25360775 | 0.86 | PTGES (0.43) | GRM2HSD11B1 | |
| SCHEMBL30494796 | 0.86 | PTGES (0.43) | GRM2HSD11B1 | |
| SCHEMBL30495211 | 0.84 | KMT2A (0.43) | DHODH | |
| SCHEMBL25362252 | 0.84 | KMT2A (0.43) | DHODH | |
| SCHEMBL25360371 | 0.83 | RXFP1 (0.40) | DHODH | |
| SCHEMBL30494942 | 0.83 | RXFP1 (0.40) | DHODH | |
| SCHEMBL25359682 | 0.83 | DHODH (0.45) | DHODH | |
| SCHEMBL30690313 | 0.83 | DHODH (0.45) | DHODH | |
| SCHEMBL25358826 | 0.82 | HSD11B1 (0.40) | DHODHHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |