Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958918 | 0.90 | L3MBTL1 (0.45) | PDE10AHTR6NPC1RAB9AL3MBTL1 | |
| SCHEMBL1357445 | 0.88 | AKR1C3 (0.47) | PDE10AHTR6RAB9AAKR1C3L3MBTL1 | |
| SCHEMBL29992656 | 0.88 | AKR1C3 (0.47) | PDE10AHTR6RAB9AAKR1C3L3MBTL1 | |
| SCHEMBL29992688 | 0.88 | AKR1C3 (0.47) | PDE10AHTR6RAB9AAKR1C3L3MBTL1 | |
| SCHEMBL31370509 | 0.84 | L3MBTL1 (0.49) | PDE10AHTR6SMN1; SMN2AKR1C3L3MBTL1 | |
| SCHEMBL31370555 | 0.84 | HTR6 (0.43) | PDE10AHTR6AKR1C3L3MBTL1MEN1 | |
| SCHEMBL31370670 | 0.83 | HTR6 (0.42) | PDE10AHTR6AKR1C3L3MBTL1MEN1 | |
| SCHEMBL23107203 | 0.82 | SRD5A2 (0.42) | PPARGPPARDPPARAL3MBTL1MAOB | |
| SCHEMBL31689015 | 0.81 | APP (0.41) | PDE10AHTR6SMPD1PPARGPPARD | |
| SCHEMBL29992649 | 0.80 | HTR6 (0.42) | PDE10AHTR6AKR1C3L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | PDE10A 3902/4885HTR6 3261/4885SMPD1 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.