Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MB | P02144 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1570132 | 0.87 | LMNA (0.52) | LMNASMN1; SMN2HSD17B10HTTL3MBTL1 | |
| SCHEMBL10882572 | 0.80 | LMNA (0.61) | LMNASMN1; SMN2HSD17B10HTTL3MBTL1 | |
| SCHEMBL3791417 | 0.79 | LMNA (0.58) | LMNAIDO1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL2728856 | 0.79 | LMNA (0.58) | LMNAIDO1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL18109247 | 0.78 | MEN1 (0.44) | LMNAIDO1SMN1; SMN2HSD17B10HTT | |
| SCHEMBL1569990 | 0.78 | LMNA (0.44) | LMNASMN1; SMN2HSD17B10HTTL3MBTL1 | |
| SCHEMBL21268291 | 0.75 | MAPKAPK2 (0.40) | CA12CA1CA9 | |
| SCHEMBL25361063 | 0.74 | KMT2A (0.60) | LMNASMN1; SMN2HSD17B10HTTALDH1A1 | |
| SCHEMBL1570394 | 0.74 | LMNA (0.40) | LMNASMN1; SMN2HSD17B10HTTL3MBTL1 | |
| SCHEMBL2894937 | 0.74 | KIF11 (0.46) | LMNAIDO1SMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904350-B1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 2023-08-23 | — | — | EP | claimed |
| CN-111989323-A | N- (cyclopropylmethyl) -5- (methylsulfonyl) -N- {1- [1- (pyrimidin-2-yl) -1H-1, 2, 4-triazol-5-yl ] ethyl } benzamide derivatives and corresponding picolinamide derivatives as pesticides | 拜耳公司 | 2020-11-24 | — | — | CN | claimed |
| CN-111989323-A | N- (cyclopropylmethyl) -5- (methylsulfonyl) -N- {1- [1- (pyrimidin-2-yl) -1H-1, 2, 4-triazol-5-yl ] ethyl } benzamide derivatives and corresponding picolinamide derivatives as pesticides | 拜耳公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-103339117-A | 1,4 oxazines as bace1 and/or bace2 inhibitors | HOFFMANN LA ROCHE | 2013-10-02 | — | — | CN | disclosed |