Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154026 | 0.82 | MEN1 (0.86) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL23109077 | 0.76 | MGLL (0.64) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL10344698 | 0.75 | KMT2A (0.59) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL1947748 | 0.75 | HSD17B10 (0.63) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL25360083 | 0.74 | LMNA (0.45) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL9342656 | 0.74 | KMT2A (0.72) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL2246735 | 0.74 | MEN1 (0.96) | KMT2AMEN1LMNASMN1; SMN2HPGD | |
| SCHEMBL1921374 | 0.72 | GAA (0.56) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL7020413 | 0.72 | PTGIR (0.48) | SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL10344645 | 0.71 | NAMPT (0.53) | KMT2AMEN1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904350-B1 | N-(CYCLOPROPYLMETHYL)-5-(METHYLSULFONYL)-N-{1-[1-(PYRIMIDIN-2-YL)-1H-1,2,4-TRIAZOL-5-YL]ETHYL}BENZAMIDE DERIVATIVES AND THE CORRESPONDING PYRIDINE-CARBOXAMIDE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 2023-08-23 | — | — | EP | claimed |