SCHEMBL25361554

SCHEMBL25361554

Cc1ccc(C(NCCCCC(NC(=O)C(NC(=O)CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)C)C(=O)Nc2ccc(O)cc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SIRT5 Q9NXA8 3/20 0.38
▸ FURIN P09958 3/20 0.35
▸ SIRT2 Q8IXJ6 8/20 0.34
▸ SIRT1 Q96EB6 6/20 0.34
▸ FOLH1 Q04609 3/20 0.33
▸ ALB P02768 1/20 0.33
▸ SIRT3 Q9NTG7 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25361536 1.00 SIRT5 (0.38) SIRT5FURINSIRT2SIRT1FOLH1
SCHEMBL25361975 0.94 FURIN (0.37) SIRT5FURINSIRT2SIRT1FOLH1
SCHEMBL25350530 0.94 FURIN (0.35) SIRT5FURINSIRT2SIRT1ALB
SCHEMBL25361987 0.94 FURIN (0.37) SIRT5FURINSIRT2SIRT1FOLH1
SCHEMBL29048536 0.93 FURIN (0.37) SIRT5FURINSIRT2SIRT1FOLH1
SCHEMBL25383060 0.93 FURIN (0.37) SIRT5FURINSIRT2SIRT1FOLH1
SCHEMBL25360091 0.93 FURIN (0.36) FURINSIRT2SIRT1ALB
SCHEMBL25360099 0.93 FURIN (0.36) FURINSIRT2SIRT1ALB
SCHEMBL25361835 0.93 FURIN (0.34) FURINSIRT2SIRT1ALBSIRT3
SCHEMBL25361983 0.90 FURIN (0.34) FURINSIRT2SIRT1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP SIRT5 2004/4885FURIN 2087/4885SIRT2 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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