Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OGT | O15294 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600970 | 1.00 | LMNA (0.39) | LMNAGAACA1CA2CA12 | |
| SCHEMBL22588417 | 0.75 | CA12 (0.47) | LMNAGAACA1CA2CA12 | |
| SCHEMBL10530946 | 0.69 | LMNA (0.49) | LMNAGAACA1CA2ALDH1A1 | |
| SCHEMBL489291 | 0.69 | LMNA (0.49) | LMNAGAACA1CA2ALDH1A1 | |
| SCHEMBL1829415 | 0.68 | CA1 (0.51) | LMNAGAACA1CA2CA12 | |
| SCHEMBL25385591 | 0.67 | LMNA (0.54) | LMNAGAACA1CA2CA12 | |
| SCHEMBL1857525 | 0.67 | HTR7 (0.44) | LMNAALDH1A1HTR7MAPTMEN1 | |
| SCHEMBL1131175 | 0.65 | ALDH1A1 (0.48) | LMNAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL6047049 | 0.64 | HPGD (0.50) | LMNAGAAALDH1A1HTR7MAPT | |
| SCHEMBL3528433 | 0.64 | LMNA (0.54) | LMNAGAAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | disclosed |