SCHEMBL25363072

SCHEMBL25363072

O=S(=O)(F)c1ccc2ccnn2c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 1/20 0.34
▸ SLC6A2 P23975 1/20 0.33
▸ SLC6A4 P31645 1/20 0.33
▸ SLC6A3 Q01959 1/20 0.33
▸ DRD2 P14416 1/20 0.32
▸ DRD4 P21917 1/20 0.32
▸ DRD3 P35462 1/20 0.32
▸ F2 P00734 2/20 0.32
▸ TMPRSS4 Q9NRS4 2/20 0.32
▸ TP53 P04637 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ ALDH3A1 P30838 1/20 0.31
▸ PDE4A P27815 1/20 0.30
▸ PDE4B Q07343 1/20 0.30
▸ PDE4C Q08493 1/20 0.30
▸ PDE4D Q08499 1/20 0.30
▸ HTR6 P50406 1/20 0.30
▸ OXTR P30559 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977343 0.81 MELK (0.39) SLC6A2SLC6A4SLC6A3
SCHEMBL30977594 0.67 DRD2 (0.37) SLC6A2SLC6A4SLC6A3DRD2DRD4
SCHEMBL22715184 0.67 DRD2 (0.41) SLC6A2SLC6A4SLC6A3DRD2DRD4
SCHEMBL22726675 0.66 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3PDE4APDE4B
SCHEMBL23938030 0.66 DRD2 (0.49) RAB9ASLC6A2SLC6A4SLC6A3DRD2
SCHEMBL25220159 0.65 KIF11 (0.38) RAB9ASLC6A2SLC6A4SLC6A3DRD2
SCHEMBL11574176 0.64 TSHR (0.56) F2TMPRSS4TP53CYP1A2CYP2D6
SCHEMBL30977328 0.63 DRD2 (0.43) SLC6A2SLC6A4SLC6A3DRD2DRD4
SCHEMBL22726718 0.63 HTR1A (0.38) RAB9ASLC6A2SLC6A4SLC6A3DRD2
SCHEMBL30977516 0.63 DRD2 (0.43) SLC6A2SLC6A4SLC6A3DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250152574-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-15 — — US disclosed
CN-119731156-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 — — CN disclosed
EP-4479384-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2024-12-25 — — EP disclosed
WO-2023154499-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152574-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP RAB9A 3939/4885SLC6A2 4281/4885SLC6A4 4240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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