SCHEMBL253659

SCHEMBL253659

C=C[C](C#N)CCCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.39
ZDHHC2 Q9UIJ5 2/20 0.39
TSHR P16473 6/20 0.36
FAAH O00519 1/20 0.36
CES1 P23141 5/20 0.36
CES2 O00748 4/20 0.36
AKR1B1 P15121 1/20 0.34
PPARG P37231 6/20 0.33
PPARD Q03181 6/20 0.33
PPARA Q07869 6/20 0.33
GPR84 Q9NQS5 5/20 0.33
HDAC11 Q96DB2 5/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33
PTPN1 P18031 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10898240 0.78 TSHR (0.36) ZDHHC20ZDHHC2TSHRFAAHCES1
SCHEMBL6545411 0.71
SCHEMBL44510 0.70
SCHEMBL8511148 0.69 TSHR (0.37) ZDHHC20ZDHHC2TSHRFAAHCES1
SCHEMBL9474926 0.69 TSHR (0.37) ZDHHC20ZDHHC2TSHRFAAHCES1
SCHEMBL3429700 0.69 CES2 (0.43) ZDHHC20ZDHHC2TSHRFAAHCES1
SCHEMBL797999 0.69 TSHR (0.46) ZDHHC20ZDHHC2TSHRFAAHCES1
SCHEMBL11392938 0.68 CES2 (0.42) TSHRCES1CES2PPARGPPARD
SCHEMBL19650486 0.68 CES2 (0.42) TSHRCES1CES2PPARGPPARD
SCHEMBL10375178 0.68 CES2 (0.42) TSHRCES1CES2PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023102600-A1 SYNTHESIS OF AMPHIPHILIC BLOCK COPOLYMERS AND POLYMERIC NANOFIBERS PRODUCED THEREFROM NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2023-06-15 WO disclosed
EP-2389395-B1 RAFT POLYMERISATION COMMW SCIENT IND RES ORG (AU) 2017-03-29 EP disclosed
US-9340498-B2 Raft polymerisation COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESERACH ORGANISATION (AU) 2016-05-17 US disclosed
US-20120004381-A1 RAFT POLYMERISATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-01-05 US disclosed
EP-2389395-A1 RAFT POLYMERISATION Commonwealth Scientific and Industrial Research Organisation (AU) 2011-11-30 EP disclosed
US-20110256644-A1 MASKS FOR MICROLITHOGRAPHY AND METHODS OF MAKING AND USING SUCH MASKS MICRON TECHNOLOGY, INC. (US) 2011-10-20 US disclosed
WO-2010083569-A1 RAFT POLYMERISATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004381-A1 RAFT POLYMERISATION OXGR1, FRG1, MSR1 ZDHHC20 675/4885ZDHHC2 279/4885TSHR 1897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.