Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552519 | 0.85 | MAPT (0.56) | DRD4MAPTKDM4EALDH1A1ADRA1D | |
| SCHEMBL26668393 | 0.85 | DRD4 (0.77) | DRD4MAPTKDM4EALDH1A1DRD2 | |
| SCHEMBL5988539 | 0.83 | MAPT (0.77) | DRD4MAPTKDM4EDRD2DRD3 | |
| SCHEMBL22532699 | 0.83 | DRD4 (0.79) | DRD4KDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL7958587 | 0.82 | POLB (0.56) | DRD4MAPTKDM4EALDH1A1CHKA | |
| SCHEMBL1244075 | 0.82 | ALDH1A1 (0.73) | MAPTKDM4EALDH1A1 | |
| SCHEMBL20639662 | 0.81 | ADRA1D (0.52) | DRD4MAPTKDM4EALDH1A1ADRA1D | |
| SCHEMBL25160501 | 0.81 | ADRA1D (0.52) | DRD4MAPTKDM4EALDH1A1ADRA1D | |
| SCHEMBL25368957 | 0.80 | ADRA1D (0.53) | DRD4MAPTKDM4EADRA1DADRA1A | |
| SCHEMBL11551844 | 0.79 | POLB (0.71) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640122-A | IKZF 2 Degradation agent, pharmaceutical composition containing degradation agent and application of degradation agent | 苏州国匡医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2023155710-A1 | IKZF2 DEGRADATION AGENT, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF | 苏州国匡医药科技有限公司 | 2023-08-24 | — | — | WO | disclosed |