Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GPR183 | P32249 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198934 | 0.91 | SIGMAR1 (0.75) | ALDH1A1KDM4ESIGMAR1HPGDDUSP3 | |
| SCHEMBL1239274 | 0.91 | HRH3 (0.74) | ALDH1A1KDM4EHRH3POLBTNIK | |
| SCHEMBL1241202 | 0.91 | ALDH1A1 (0.68) | ALDH1A1KDM4EHRH3TNIKCYP2D6 | |
| SCHEMBL5257237 | 0.89 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDDUSP3PTPN5 | |
| SCHEMBL578497 | 0.89 | LMNA (0.67) | ALDH1A1KDM4EHPGDLMNAPOLB | |
| SCHEMBL10502907 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KDM4EHRH3HPGDDUSP3 | |
| SCHEMBL1241906 | 0.89 | HRH3 (0.78) | ALDH1A1KDM4EHRH3POLBTNIK | |
| Hydrochloric Acid SCHEMBL28582354 | 0.89 | HRH3 (0.71) | ALDH1A1KDM4EHRH3POLBTNIK | |
| Hydrochloric Acid SCHEMBL10508296 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KDM4EHRH3HPGDDUSP3 | |
| SCHEMBL10598914 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KDM4ESIGMAR1HRH3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241852-B2 | Unsymmetrical cyanine dimer compounds and their application | Life Technologies Corporation (US) | 2012-08-14 | — | — | US | disclosed |
| US-8242251-B2 | Unsymmetrical cyanine dimer compounds and their application | Life Technologies Corporation (US) | 2012-08-14 | — | — | US | disclosed |
| US-20110143337-A1 | UNSYMMETRICAL CYANINE DIMER COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110124085-A1 | UNSYMMETRICAL CYANINE DIMER COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation (US) | 2011-05-26 | — | — | US | disclosed |
| US-7888136-B2 | Comprises benzazolium, pyridinium, or quinolinium connected by methine bridge; reporter molecules for detection of RNA in presence of DNA; solid phase synthesis; kits | Life Technologies Corporation (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080199875-A1 | UNSYMMETRICAL CYANINE DIMER COMPOUNDS AND THEIR APPLICATION | INVITROGEN CORPORATION (US) | 2008-08-21 | — | — | US | disclosed |
| US-20050074796-A1 | Unsymmetrical cyanine dimer compounds and their application | MOLECULAR PROBES, INC. | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080199875-A1 | UNSYMMETRICAL CYANINE DIMER COMPOUNDS AND THEIR APPLICATION | NSUN2, NSUN3, TRDMT1 | ALDH1A1 3546/4885KDM4E 943/4885SIGMAR1 354/4885 |
| US-20110124085-A1 | UNSYMMETRICAL CYANINE DIMER COMPOUNDS AND THEIR APPLICATION | NSUN2, NSUN3, TRDMT1 | ALDH1A1 3546/4885KDM4E 943/4885SIGMAR1 354/4885 |
| US-20050074796-A1 | Unsymmetrical cyanine dimer compounds and their application | NSUN2, NSUN3, TRDMT1 | ALDH1A1 3546/4885KDM4E 943/4885SIGMAR1 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.