Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.35 |
| ▸ | RXRA | P19793 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25366989 | 1.00 | GPR119 (0.42) | GPR119DPP4MEN1KMT2AGRM5 | |
| SCHEMBL29035461 | 0.87 | UCHL1 (0.46) | GPR119MEN1KMT2AUCHL1NR1H2 | |
| SCHEMBL29035464 | 0.87 | UCHL1 (0.46) | GPR119MEN1KMT2AUCHL1NR1H2 | |
| SCHEMBL25362732 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL25362727 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL29880634 | 0.83 | GPR119 (0.42) | GPR119DPP4MEN1KMT2AGRM5 | |
| SCHEMBL23452587 | 0.83 | GPR119 (0.42) | GPR119DPP4MEN1KMT2AGRM5 | |
| SCHEMBL23452582 | 0.83 | GPR119 (0.42) | GPR119DPP4MEN1KMT2AGRM5 | |
| SCHEMBL25363576 | 0.82 | DPP4 (0.41) | GPR119DPP4MEN1KMT2AGRM5 | |
| SCHEMBL25363581 | 0.82 | DPP4 (0.41) | GPR119DPP4MEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |