Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979567 | 0.86 | MAPT (0.67) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL31336691 | 0.80 | CHIA (0.54) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL3846632 | 0.79 | SCD5 (0.58) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL15979596 | 0.79 | ME2 (0.64) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL8312600 | 0.79 | NOTUM (0.49) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL2114062 | 0.79 | MAPT (0.61) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL15968389 | 0.78 | TSHR (0.54) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL24434520 | 0.78 | CMA1 (0.56) | TSHRHSD17B10GFERKMT2AALDH1A1 | |
| SCHEMBL13727501 | 0.77 | NPC1 (0.59) | HSD17B10GFERKMT2AALDH1A1LMNA | |
| SCHEMBL11696465 | 0.76 | CMA1 (0.55) | TSHRHSD17B10KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1602191-A | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2005-03-30 | — | — | CN | claimed |
| CN-116640122-A | IKZF 2 Degradation agent, pharmaceutical composition containing degradation agent and application of degradation agent | 苏州国匡医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2023155710-A1 | IKZF2 DEGRADATION AGENT, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF | 苏州国匡医药科技有限公司 | 2023-08-24 | — | — | WO | disclosed |
| CN-1326519-C | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2007-07-18 | — | — | CN | disclosed |
| CN-1602191-A | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2005-03-30 | — | — | CN | disclosed |