Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520046 | 1.00 | DYRK1A (0.44) | DYRK1AALDH1A3TRIM33TGFBR1TGFBR2 | |
| SCHEMBL18042041 | 0.84 | TGFBR1 (0.52) | DYRK1ATGFBR1TGFBR2ALDH1A1MAPT | |
| SCHEMBL18057147 | 0.84 | TGFBR1 (0.58) | DYRK1ATGFBR1TGFBR2ALDH1A1MAPT | |
| SCHEMBL18041581 | 0.84 | DYRK1A (0.47) | DYRK1ATGFBR1TGFBR2ADORA2AALDH1A1 | |
| SCHEMBL30519842 | 0.83 | ALDH1A1 (0.45) | ALDH1A3TGFBR1ADORA2AALDH1A1ADORA1 | |
| SCHEMBL25365138 | 0.83 | ALDH1A1 (0.45) | ALDH1A3TGFBR1ADORA2AALDH1A1ADORA1 | |
| SCHEMBL18041778 | 0.82 | DYRK1A (0.45) | DYRK1AALDH1A3TRIM33TGFBR1TGFBR2 | |
| SCHEMBL29677055 | 0.82 | DYRK1A (0.45) | DYRK1AALDH1A3TRIM33TGFBR1TGFBR2 | |
| SCHEMBL29677091 | 0.81 | RET (0.46) | DYRK1ATGFBR1TGFBR2ADORA2AALDH1A1 | |
| SCHEMBL18041923 | 0.81 | RET (0.46) | DYRK1ATGFBR1TGFBR2ADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-07-31 | — | — | US | disclosed |
| WO-2023144559-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | AdoRx Therapeutics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | ADORA2B, ADORA2A, ADORA1 | DYRK1A 1526/4885ALDH1A3 1483/4885TRIM33 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.