Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SDHB | P21912 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138661 | 1.00 | KDM4E (0.45) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL29036325 | 0.89 | XDH (0.47) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL31656077 | 0.89 | XDH (0.47) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL31254967 | 0.87 | ALDH1A1 (0.44) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL29194231 | 0.87 | NOTUM (0.53) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL31409842 | 0.87 | NOTUM (0.53) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL29229221 | 0.87 | KDM4E (0.47) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL29131103 | 0.84 | NOTUM (0.43) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL29225262 | 0.83 | NPC1 (0.49) | KDM4ELMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL29036274 | 0.83 | VCAM1 (0.46) | KDM4ELMNAHTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-118525022-A | Azacyclo derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-117263944-A | Ubiquitin-specific protease 1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2023143424-A1 | AZACYCLIC DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-116514845-A | USP1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-08-01 | — | — | CN | disclosed |