Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31570599 | 0.75 | SMPD3 (0.53) | SMPD3KMT2AMEN1POLBGAA | |
| SCHEMBL939415 | 0.75 | SMPD3 (0.53) | SMPD3KMT2AMEN1POLBGAA | |
| SCHEMBL25370544 | 0.74 | LGMN (0.54) | KMT2AMEN1GAAALDH1A1HPGD | |
| SCHEMBL29762445 | 0.72 | SMPD3 (0.47) | SMPD3KMT2AMEN1POLBGAA | |
| SCHEMBL31052606 | 0.72 | MAPT (0.53) | SMPD3KMT2AMEN1POLBGAA | |
| SCHEMBL24195931 | 0.72 | SMPD3 (0.47) | SMPD3KMT2AMEN1POLBGAA | |
| SCHEMBL4647849 | 0.72 | ALDH1A1 (0.55) | KMT2AMEN1POLBGAAKDM4E | |
| SCHEMBL27847541 | 0.71 | SMN1; SMN2 (0.47) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31052704 | 0.71 | MAPT (0.51) | SMPD3GAAKDM4EHSD17B10MAPT | |
| SCHEMBL25373094 | 0.70 | RAB9A (0.52) | KMT2AMEN1GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482831-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | Satya Therapeutics, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161782-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYARX PHARMA INNOVATIONS PVT LTD (IN) | 2023-08-31 | — | — | WO | disclosed |