SCHEMBL253732

SCHEMBL253732

O=Cc1ccc(N2CCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 1.00
TRIM33 Q9UPN9 1/20 1.00
ALDH1A1 P00352 7/20 0.96
SMN1; SMN2 Q16637 3/20 0.96
KDM4E B2RXH2 1/20 0.96
PTGS2 P35354 3/20 0.58
ACHE P22303 3/20 0.56
ALDH1A3 P47895 3/20 0.53
MEN1 O00255 2/20 0.52
MAPT P10636 2/20 0.52
KMT2A Q03164 2/20 0.52
BCHE P06276 1/20 0.50
RECQL P46063 1/20 0.49
KDM4C Q9H3R0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL896372 0.98 ALDH1A1 (1.00) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL160596 0.98 ALDH1A1 (1.00) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL7180854 0.95 TRIM24 (0.91) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL32688383 0.94 TRIM24 (0.88) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL22579326 0.92 ALDH1A1 (0.89) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL2561698 0.91 TRIM24 (0.83) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL3077544 0.91 TRIM24 (0.83) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL18821776 0.89 TRIM24 (0.79) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL18821765 0.87 ALDH1A1 (0.79) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E
SCHEMBL15850279 0.83 TRIM24 (0.70) TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 895 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079883-A Long alkyl chain lysosome fluorescent probe and method, composition, preparation, kit and application thereof 2026-05-26 CN claimed
CN-119352168-A Organic nonlinear crystal material for thermally enhanced frequency multiplication signal, preparation method and application thereof 中国科学院福建物质结构研究所 2025-01-24 CN claimed
CN-114605371-B Benzopyran derivative BP-III and synthetic method and application thereof 山西大学 2024-05-28 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
CN-115073423-A Quinoline derivative and preparation method and application thereof 广东工业大学 2022-09-20 CN claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
CN-114605371-A Benzopyran derivative BP-III and synthesis method and application thereof 山西大学 2022-06-10 CN claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
CN-112920113-A Beta amyloid-targeted fluorescent probe, preparation method thereof and application thereof in Alzheimer's disease 华南理工大学 2021-06-08 CN claimed
WO-2004022016-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-18 WO claimed
WO-2003106431-A2 NOVEL HEXAHYDRO-PYRIDAZINE-3-CARBOCYLIC ACID HYDRAZIDE OR HYDRAZONE DERIVATIVES, COMBINATORIAL LIBRARIES CONTAINING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR PREPARING SAME AVENTIS PHARMA S.A. (FR) 2003-12-24 WO claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-1200051-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-05-02 EP claimed
WO-2001013866-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-03-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO TRIM24 2169/4885TRIM33 1420/4885ALDH1A1 111/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO TRIM24 2169/4885TRIM33 1420/4885ALDH1A1 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.