SCHEMBL896372

SCHEMBL896372

O=Cc1ccc(N2CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 1.00
KDM4E B2RXH2 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
TRIM24 O15164 1/20 0.96
TRIM33 Q9UPN9 1/20 0.96
PTGS2 P35354 3/20 0.56
ACHE P22303 2/20 0.55
ALDH1A3 P47895 3/20 0.53
MAPT P10636 5/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
RECQL P46063 2/20 0.52
NPC1 O15118 1/20 0.52
USP2 O75604 1/20 0.52
TP53 P04637 1/20 0.52
POLB P06746 1/20 0.52
GAA P10253 1/20 0.52
THRB P10828 1/20 0.52
ALOX15 P16050 1/20 0.52
HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160596 1.00 ALDH1A1 (1.00) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL253732 0.98 TRIM24 (1.00) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL22579326 0.94 ALDH1A1 (0.89) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL7180854 0.93 TRIM24 (0.91) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL32688383 0.92 TRIM24 (0.88) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL18821765 0.89 ALDH1A1 (0.79) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL3077544 0.89 TRIM24 (0.83) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL2561698 0.89 TRIM24 (0.83) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL18821776 0.87 TRIM24 (0.79) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL18941350 0.83 ALDH1A1 (0.71) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 694 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504612-A Quinazoline stilbene derivative and preparation method and application thereof 中国海洋大学 2025-02-25 CN claimed
CN-118084825-A Conjugated molecular tool for piperidine coupled vitamin and preparation method and application thereof 江西广源新材料有限公司 2024-05-28 CN claimed
CN-117800982-A Near infrared fluorescent probe, preparation method thereof and dual-response detection Cu 2+ And use in Abeta aggregates 河南大学 2024-04-02 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
CN-115073423-B Quinoline derivative and preparation method and application thereof 广东工业大学 2023-08-01 CN claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
WO-2022255764-A1 NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE 주식회사 에즈큐리스 2022-12-08 WO claimed
CN-115073423-A Quinoline derivative and preparation method and application thereof 广东工业大学 2022-09-20 CN claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
EP-1433469-A1 Composition for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2004022016-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-18 WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1200051-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-05-02 EP claimed
WO-2001013866-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-03-01 WO claimed
EP-0202164-B1 (BENZOYL-4-PIPERIDINO)-2-PHENYL-1-ALKANOL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES SYNTHELABO (FR) 1989-02-08 EP claimed
EP-0202164-A1 (Benzoyl-4-piperidino)-2-phenyl-1-alkanol derivatives, their preparation and their use as medicines SYNTHELABO (FR) 1986-11-20 EP claimed
US-4582903-A Synthesis of unsaturated hydantoins with an inexpensive catalyst STAUFFER CHEMICAL COMPANY (US) 1986-04-15 US claimed
US-4345072-A Process for the production of 5-arylidene hydantoins (B) DEGUSSA AG (DE) 1982-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ALDH1A1 111/4885KDM4E 1526/4885SMN1; SMN2 4757/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO ALDH1A1 111/4885KDM4E 1526/4885SMN1; SMN2 4757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.