SCHEMBL253735

SCHEMBL253735

C=CC[Si](CC=C)(CC=C)c1ncc[nH]1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7049007 0.71 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2ALOX15
SCHEMBL28443985 0.68 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2ALOX15
SCHEMBL1374565 0.66 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2ALOX15
SCHEMBL28449449 0.65 CYP1A2 (0.41) ALDH1A1SMN1; SMN2
SCHEMBL29022393 0.65 ALOX15 (0.41) ALOX15
SCHEMBL7559333 0.65
SCHEMBL11317 0.65
Hydrochloric Acid SCHEMBL3806550 0.64
SCHEMBL6159345 0.64
Ammonia Solution, Strong SCHEMBL8665541 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62059295-A None JP disclosed
JP-62084099-A None JP disclosed
JP-55062073-A None JP disclosed
JP-8245762-A None JP disclosed
EP-3786151-B1 METHOD FOR PRODUCING AMIDE COMPOUND CHUBU UNIV EDUCATIONAL FOUNDATION (JP) 2023-06-07 EP disclosed
US-20210147473-A1 METHOD FOR PRODUCING AMIDE COMPOUND CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2021-05-20 US disclosed
EP-3786151-A1 METHOD FOR PRODUCING AMIDE COMPOUND Chubu University Educational Foundation (JP) 2021-03-03 EP disclosed
CN-112020492-A Process for producing amide compound 学校法人中部大学 2020-12-01 CN disclosed
US-10358526-B2 Moisture-curing polyether carbonate containing alkoxysilyl groups COVESTRO DEUTSCHLAND AG (DE) 2019-07-23 US disclosed
US-20170313816-A1 MOISTURE-CURING POLYETHER CARBONATE CONTAINING ALKOXYSILYL GROUPS COVESTRO DEUTSCHLAND AG (DE) 2017-11-02 US disclosed
EP-0527069-A1 Derivatives of pyrrolidine and thiazolidine, their preparation, and pharmaceutical compositions containing them Aventis Pharma S.A. (FR) 1993-02-10 EP disclosed
WO-1993001167-A1 PYRROLIDINE AND THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME RHONE-POULENC RORER S.A. (FR) 1993-01-21 WO disclosed
US-5145846-A Skin disorders, leukemia, sebaceous gland disorders HOFFMANN-LA ROCHE INC. (US) 1992-09-08 US disclosed
US-5087619-A For treatment of skin or gland disorders; antitumor agents HOFFMAN-LA ROCHE INC. (US) 1992-02-11 US disclosed
EP-0382935-A1 2-(1H-imidazol-4(5)-yl)-3,4-dihydro-2H-1-benzothiopyran FARMITALIA CARLO ERBA S.r.l. (IT) 1990-08-22 EP disclosed
JP-S6284099-A NOVEL PRODUCTION OF PEPTIDE SUNTORY LTD 1987-04-17 JP disclosed
JP-S6259295-A NOVEL PROCESS FOR PRODUCING PEPTIDE SUNTORY LTD 1987-03-14 JP disclosed
JP-S5562073-A PRODUCTION OF IMIDAZOLE SUMITOMO CHEM CO LTD 1980-05-10 JP disclosed
JP-S06259295-A 0001-01-01 JP disclosed
JP-S06284099-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147473-A1 METHOD FOR PRODUCING AMIDE COMPOUND ASNS, VIP, BCAT2 ALDH1A1 2505/4885SMN1; SMN2 2484/4885ALOX15 2610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.