Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248308 | 0.82 | PNP (0.43) | PDCD1CD274PARP1SIGMAR1 | |
| SCHEMBL25372203 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL25375192 | 0.79 | ALDH1A1 (0.32) | ALDH1A1SIGMAR1HTR6 | |
| SCHEMBL25373466 | 0.78 | CYP2D6 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL25374741 | 0.75 | MAPT (0.36) | KDM4EALDH1A1 | |
| SCHEMBL25378073 | 0.73 | ALDH1A1 (0.33) | PDCD1CD274PARP1KDM4EALDH1A1 | |
| SCHEMBL25376293 | 0.69 | PDCD1 (0.40) | PDCD1CD274ALDH1A1PIK3CD | |
| SCHEMBL25377604 | 0.69 | CACNA1G (0.38) | — | |
| SCHEMBL25375825 | 0.66 | KDM4E (0.31) | KDM4E | |
| SCHEMBL25376410 | 0.65 | PKM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4484426-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | Sunshine Lake Pharma Co., Ltd. (CN) | 2025-01-01 | — | — | EP | disclosed |
| CN-116693527-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |