SCHEMBL25374352

SCHEMBL25374352

CC(CCO)N/C=C(\C(=O)O)C(=O)c1cc(F)c(F)c(F)c1F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25379757 0.90 CES2 (0.31) SMN1; SMN2TDP1
SCHEMBL9746643 0.90 CES2 (0.31) SMN1; SMN2TDP1
SCHEMBL9748463 0.90 CES2 (0.31) SMN1; SMN2TDP1
SCHEMBL10516094 0.80
SCHEMBL10515038 0.80
SCHEMBL6511932 0.76 MEN1 (0.36) SMN1; SMN2TDP1
SCHEMBL5534138 0.76 MEN1 (0.36) SMN1; SMN2TDP1
SCHEMBL25373513 0.76 CES2 (0.32)
SCHEMBL25373606 0.76 CES2 (0.32)
SCHEMBL2191174 0.75 SMN1; SMN2 (0.36) SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023158862-A2 STIMULATOR OF INTERFERON GENES (STING) MODULATORS, AND COMPOSITIONS AND METHODS THEREOF GEODE THERAPEUTICS INC. (US) 2023-08-24 WO disclosed