Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748463 | 1.00 | CES2 (0.31) | CES2CES1SMN1; SMN2TDP1 | |
| SCHEMBL25379757 | 1.00 | CES2 (0.31) | CES2CES1SMN1; SMN2TDP1 | |
| SCHEMBL25374352 | 0.90 | SMN1; SMN2 (0.30) | SMN1; SMN2TDP1 | |
| SCHEMBL10516094 | 0.89 | — | — | |
| SCHEMBL10515038 | 0.89 | — | — | |
| SCHEMBL6511932 | 0.85 | MEN1 (0.36) | SMN1; SMN2TDP1 | |
| SCHEMBL5534138 | 0.85 | MEN1 (0.36) | SMN1; SMN2TDP1 | |
| SCHEMBL3611468 | 0.81 | KDM4E (0.42) | — | |
| SCHEMBL3611465 | 0.81 | KDM4E (0.42) | — | |
| SCHEMBL2191174 | 0.77 | SMN1; SMN2 (0.36) | CES2CES1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489733-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1990012799-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1990-11-01 | — | — | WO | disclosed |