Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534138 | 1.00 | MEN1 (0.36) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL26365723 | 0.87 | MEN1 (0.35) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL10392582 | 0.86 | MEN1 (0.37) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL9748463 | 0.85 | CES2 (0.31) | TDP1SMN1; SMN2 | |
| SCHEMBL9746643 | 0.85 | CES2 (0.31) | TDP1SMN1; SMN2 | |
| SCHEMBL25379757 | 0.85 | CES2 (0.31) | TDP1SMN1; SMN2 | |
| SCHEMBL9510054 | 0.85 | KMT2A (0.35) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL10683398 | 0.84 | CYP2D6 (0.37) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL13502976 | 0.83 | MEN1 (0.39) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL26197015 | 0.82 | MEN1 (0.33) | MEN1KMT2ANPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123746-A1 | METHODS FOR PREPARATION OF LEVOFLOXACIN AND OFLOXACIN | ZHE JIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) | 2005-12-29 | — | — | WO | disclosed |
| US-4958045-A | ENAMINES, BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| US-4859773-A | Preparation of 1,8-bridged 4-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| US-4762831-A | PROMOTE ANIMAL GROWTH | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0206101-A1 | Process for the preparation of 1,8-bridged 4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |