Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374519 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHPGDGSK3BDYRK1A | |
| SCHEMBL25376440 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL25376436 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL25375616 | 0.83 | GSK3B (0.37) | SMN1; SMN2LMNAHPGDGSK3BDYRK1A | |
| SCHEMBL25375614 | 0.83 | GSK3B (0.37) | SMN1; SMN2LMNAHPGDGSK3BDYRK1A | |
| SCHEMBL25376747 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL25376743 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| Hydrochloric Acid SCHEMBL29099900 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| Hydrochloric Acid SCHEMBL29099902 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL29093747 | 0.73 | ATM (0.36) | SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4484426-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | Sunshine Lake Pharma Co., Ltd. (CN) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |