Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375616 | 1.00 | GSK3B (0.37) | GSK3BDYRK1AAAK1RORCKDM1A | |
| SCHEMBL25374512 | 0.83 | SMN1; SMN2 (0.41) | GSK3BDYRK1ARORCKDM1ACNR2 | |
| SCHEMBL25374519 | 0.83 | SMN1; SMN2 (0.41) | GSK3BDYRK1ARORCKDM1ACNR2 | |
| SCHEMBL25376152 | 0.78 | L3MBTL1 (0.34) | SMN1; SMN2GRNSORT1HTR1ACYP2D6 | |
| SCHEMBL25376158 | 0.78 | L3MBTL1 (0.34) | SMN1; SMN2GRNSORT1HTR1ACYP2D6 | |
| SCHEMBL30159225 | 0.72 | GPR119 (0.43) | GSK3BDYRK1ASMN1; SMN2GRNSORT1 | |
| SCHEMBL16326290 | 0.71 | CTSK (0.42) | TDP1ALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL25375678 | 0.71 | CTSK (0.38) | AAK1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL25375682 | 0.71 | CTSK (0.38) | AAK1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL20267444 | 0.69 | LMNA (0.50) | SMN1; SMN2GRNSORT1CYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4484426-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | Sunshine Lake Pharma Co., Ltd. (CN) | 2025-01-01 | — | — | EP | disclosed |
| CN-116693527-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |