Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376440 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL25374519 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL25374512 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL25376743 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL25376747 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| Hydrochloric Acid SCHEMBL29099902 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| Hydrochloric Acid SCHEMBL29099900 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL29093582 | 0.72 | TLR8 (0.61) | LMNAHPGD | |
| SCHEMBL3318854 | 0.72 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHPGDGRNSORT1 | |
| SCHEMBL19918748 | 0.72 | L3MBTL1 (0.40) | SMN1; SMN2LMNAHPGDGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160527-A1 | PYRIMIDO AROMATIC RING COMPOUND AND USE THEREOF IN DRUG | 广东东阳光药业股份有限公司 | 2023-08-31 | — | — | WO | disclosed |