Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535000 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL3741628 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL23275255 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL28932011 | 0.88 | ALDH1A1 (0.46) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL14801236 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL14801909 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL20479381 | 0.84 | CPB1 (0.45) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL20974421 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL2540745 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAACTSKCPB1CTSL | |
| SCHEMBL18342363 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAACTSKCPB1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044068-B2 | Aminopyrrolidine compound | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-10-25 | — | — | US | disclosed |