Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.36 |
| ▸ | LATS1 | O95835 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30482474 | 1.00 | LIMK1 (0.56) | LIMK1NUDT1NPC1ALDH1A1MAPT | |
| SCHEMBL16513325 | 0.79 | LIMK1 (0.56) | LIMK1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL29993395 | 0.79 | ALDH1A1 (0.53) | LIMK1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2404342 | 0.79 | ALDH1A1 (0.53) | LIMK1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL26192388 | 0.77 | CYP2A6 (0.51) | LIMK1NUDT1LOXL2PRKCBPRKCH | |
| SCHEMBL15641400 | 0.76 | CLK1 (0.43) | LIMK1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL17836550 | 0.72 | KDM4E (0.64) | NUDT1NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL16513215 | 0.72 | LIMK1 (1.00) | LIMK1ALDH1A1KDM4EMAPK14 | |
| SCHEMBL31301232 | 0.72 | NUDT1 (0.57) | NUDT1LOXL2LATS1LATS2 | |
| SCHEMBL5960025 | 0.72 | CSNK2A1 (0.56) | LIMK1NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170107-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. | 2025-05-29 | — | — | US | disclosed |
| EP-4469035-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | Bridgene Biosciences, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146786-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146786-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250170107-A1 | IMIDAZOPYRIDINE INHIBITORS OF TYROSINE KINASE | ABL1, LCK, SRC | LIMK1 438/4885NUDT1 800/4885NPC1 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.