Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.51 |
| ▸ | MPL | P40238 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 5/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404342 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4ELIMK1MPLNPC1 | |
| SCHEMBL11953304 | 0.81 | LIMK1 (0.54) | ALDH1A1KDM4ELIMK1NPC1MAPT | |
| SCHEMBL25375220 | 0.79 | LIMK1 (0.56) | ALDH1A1KDM4ELIMK1NPC1MAPT | |
| SCHEMBL30482474 | 0.79 | LIMK1 (0.56) | ALDH1A1KDM4ELIMK1NPC1MAPT | |
| SCHEMBL15641400 | 0.79 | CLK1 (0.43) | ALDH1A1KDM4ELIMK1NPC1MAPT | |
| SCHEMBL19981533 | 0.78 | LIMK1 (0.55) | ALDH1A1KDM4ELIMK1NPC1MAPT | |
| SCHEMBL30513213 | 0.78 | LIMK1 (0.72) | ALDH1A1KDM4ELIMK1NPC1MAPT | |
| SCHEMBL5536337 | 0.78 | CASR (0.42) | ALDH1A1KDM4EMPLNPC1FEN1 | |
| SCHEMBL38544 | 0.78 | LIMK1 (0.72) | ALDH1A1KDM4ELIMK1NPC1MAPT | |
| SCHEMBL5536331 | 0.78 | KDM4E (0.41) | ALDH1A1KDM4EMPLNPC1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993595-B2 | Compounds | MISSION THERAPEUTICS LIMITED (GB) | 2024-05-28 | — | — | US | disclosed |
| US-20230052191-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2023-02-16 | — | — | US | disclosed |
| US-11472798-B2 | Compounds | MISSION THERAPEUTICS LTD (GB) | 2022-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11472798-B2 | Compounds | UCHL1, UCHL3, UCHL5 | ALDH1A1 300/4885KDM4E 175/4885LIMK1 3707/4885 |
| US-11993595-B2 | Compounds | UCHL1, UCHL3, UCHL5 | ALDH1A1 300/4885KDM4E 175/4885LIMK1 3707/4885 |
| US-20230052191-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | ALDH1A1 285/4885KDM4E 178/4885LIMK1 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.