SCHEMBL25375770

SCHEMBL25375770

CC(CO)(CO)CO.Cc1ccc(F)cc1C1CC(=O)CC(=O)C1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 4/20 0.39
SLC9A2 Q9UBY0 4/20 0.39
SLC9A3 P48764 2/20 0.39
TP53 P04637 1/20 0.34
RECQL P46063 1/20 0.34
NR3C1 P04150 1/20 0.33
HTR7 P34969 1/20 0.33
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
MAP3K14 Q99558 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
OPRL1 P41146 1/20 0.30
CHRM3 P20309 1/20 0.30
MEP1B Q16820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25377118 0.90 OPRL1 (0.40) SLC9A1SLC9A2SLC9A3TP53RECQL
SCHEMBL6794592 0.87 SLC9A1 (0.43) SLC9A1SLC9A2SLC9A3TP53RECQL
SCHEMBL25375464 0.87 SLC9A1 (0.38) SLC9A1SLC9A2SLC9A3TP53RECQL
SCHEMBL25378965 0.84 TP53 (0.34) TP53RECQLGAAMAPT
SCHEMBL25375633 0.82 TP53 (0.35) TP53RECQLGAAMAPT
SCHEMBL12958096 0.81 SLC9A1 (0.45) SLC9A1SLC9A2SLC9A3HTR7
SCHEMBL25375621 0.81 TP53 (0.47) TP53RECQLGAAMAPT
SCHEMBL29008633 0.79 RIPK1 (0.39) GAAMAPT
SCHEMBL25376661 0.78 GRM7 (0.42) TP53RECQLGAAMAPT
SCHEMBL25373836 0.77 MAPT (0.40) TP53RECQLGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399510-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-14 US disclosed
EP-4239010-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-06 EP disclosed
CN-116323753-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-06-23 CN disclosed
CN-115996931-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-04-21 CN disclosed