Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25373947 | 0.94 | TRPM8 (0.46) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25376252 | 0.91 | MEN1 (0.44) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25373573 | 0.89 | TRPM8 (0.42) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25376218 | 0.83 | ALDH1A1 (0.42) | TRPM8ALDH1A1KMT2ATSHRMAPK1 | |
| SCHEMBL25376774 | 0.81 | TRPM8 (0.41) | TRPM8ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL25374455 | 0.80 | TSPO (0.46) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25378150 | 0.80 | HDAC1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25375679 | 0.79 | EGFR (0.44) | ALDH1A1TSHRMAPK1LMNAATM | |
| SCHEMBL25376959 | 0.79 | MEN1 (0.42) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Ammonia Solution, Strong SCHEMBL25375174 | 0.78 | MAPK1 (0.43) | ALDH1A1MEN1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |