Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247314 | 0.81 | RAB9A (0.54) | P2RX7MTORKCNH2RAB9ALSS | |
| SCHEMBL15682657 | 0.78 | MTOR (0.52) | P2RX7MTORLSSALDH1A1HDAC3 | |
| SCHEMBL5556152 | 0.77 | BCHE (0.64) | TEAD1HRH3RAB9AALDH1A1KMT2A | |
| SCHEMBL3417449 | 0.76 | LSS (0.56) | P2RX7MTORKCNH2LSSHDAC3 | |
| SCHEMBL4576236 | 0.76 | MTOR (0.54) | P2RX7MTORLSSHDAC3HDAC1 | |
| SCHEMBL4979582 | 0.76 | SLC6A5 (0.59) | TEAD1KCNH2RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL218521 | 0.76 | BCHE (0.62) | TEAD1HRH3RAB9AALDH1A1KMT2A | |
| SCHEMBL14342817 | 0.76 | EPHX1 (0.45) | TEAD1KCNH2HRH3RAB9ANPC1 | |
| SCHEMBL20593592 | 0.76 | HDAC6 (0.69) | HDAC1HDAC8HDAC6 | |
| SCHEMBL24575984 | 0.76 | MTOR (0.69) | MTORLSSSMN1; SMN2KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146987-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |