SCHEMBL25379366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25255518	0.91	AR (0.37)	MAPTALDH1A1ARTEAD1TEAD4
	SCHEMBL25378346	0.87	KMT2A (0.35)	MAPTALDH1A1KMT2ATEAD1TEAD4
	SCHEMBL25376335	0.85	CASP6 (0.40)	TEAD1TEAD4TEAD2TEAD3KDR
	SCHEMBL25253758	0.85	KDR (0.35)	MAPTALDH1A1KMT2ATEAD1TEAD4
	SCHEMBL30561703	0.83	CACNA1H (0.40)	ARTRPA1
	SCHEMBL25380752	0.83	CACNA1H (0.40)	ARTRPA1
	SCHEMBL25378701	0.83	KDM4E (0.35)	MAPTALDH1A1TEAD1TEAD4TEAD2
	SCHEMBL25378308	0.83	PRKAA2 (0.37)	MAPTALDH1A1ARTRPA1HPGD
	SCHEMBL25380630	0.83	BCL2A1 (0.42)	MAPTALDH1A1MAPK1HPGDKDM4E
	SCHEMBL30561682	0.83	PRKAA2 (0.37)	MAPTALDH1A1ARTRPA1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.