Hypoxanthine

Hypoxanthine

SCHEMBL25382

Oc1ncnc2nc[nH]c12

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
PI4KA P42356 2/20 0.57
PI4K2B Q8TCG2 2/20 0.57
PI4K2A Q9BTU6 2/20 0.57
PI4KB Q9UBF8 2/20 0.57
LRRK2 Q5S007 2/20 0.57
DRD3 P35462 1/20 0.57
XDH P47989 1/20 0.57
G6PD P11413 1/20 0.55
PDPK1 O15530 2/20 0.52
TP53 P04637 2/20 0.52
HSD17B10 Q99714 2/20 0.52
CHEK1 O14757 1/20 0.52
AURKA O14965 1/20 0.52
CHEK2 O96017 1/20 0.52
HSP90AA1 P07900 1/20 0.52
HSP90AB1 P08238 1/20 0.52
PRKACA P17612 1/20 0.52
CCNE1 P24864 1/20 0.52
CDK2 P24941 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hypoxanthine SCHEMBL6673817 0.98 LMNA (0.55) LMNAPI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL1230632 0.98 LMNA (0.55) LMNAPI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL560393 0.98 PI4KA (0.59) LMNAPI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL29060925 0.89 PI4KA (0.52) LMNAPI4KAPI4K2BPI4K2API4KB
Hypoxanthine SCHEMBL7157944 0.86 TSHR (0.50) LMNAPI4KAPI4K2BPI4K2API4KB
SCHEMBL11903083 0.77 CYP3A4 (0.53) LMNAPI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL385842 0.74 LMNA (0.92) LMNAPI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL8111 0.73 PI4KA (1.00) LMNAPI4KAPI4K2BPI4K2API4KB
SCHEMBL532632 0.73 PI4KA (0.57) LMNAPI4KAPI4K2BPI4K2API4KB
Mercaptopurine Anhydrous SCHEMBL8844 0.73 LMNA (0.57) LMNAPI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 147878 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
CN-122081155-A Pediococcus acidilactici TC-4 capable of degrading nucleoside, purine and uric acid simultaneously and application thereof 2026-05-26 CN claimed
CN-122080194-A Anti-H5 subtype avian influenza virus hemagglutinin protein monoclonal antibody 1F8 and application thereof 2026-05-26 CN claimed
CN-122095092-A Inhibitor for inhibiting inhibin Beta E gene expression and application thereof 2026-05-26 CN claimed
US-12637489-B2 Silicon containing modified nucleotide analogs Singular Genomics Systems, Inc. (US) 2026-05-26 US claimed
EP-0076647-A2 Culture media for cells originating from the immune system HANA Biologics Incorporated (US) 1983-04-13 EP claimed
US-4371613-A TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE AJINOMOTO COMPANY INCORPORATED (JP) 1983-02-01 US claimed
EP-0009154-B1 COMPLEXES OF 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITIONS CONTAINING THE COMPLEXES AS ACTIVE INGREDIENTS Newport Pharmaceuticals International, Inc. (US) 1982-12-08 EP claimed
US-4341868-A PEROXIDATION; COLORIMETRY; QUANTITAVE ANALYSIS; ONE-STEP; ENTEROBACTER KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-07-27 US claimed
US-4266048-A Synthesis of analogs of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-05-05 US claimed
EP-0016845-A1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1980-10-15 EP claimed
US-4218535-A Determination of enzyme substrate concentration BECKMAN INSTRUMENTS, INC. (US) 1980-08-19 US claimed
EP-0009154-A1 Complexes of 9-hydroxyalkyl-purines, processes for preparing them and therapeutical compositions containing the complexes as active ingredients Newport Pharmaceuticals International, Inc. (US) 1980-04-02 EP claimed
US-4108804-A Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel SEITA TORU 1978-08-22 US claimed
US-3939089-A PEROXYSULFATE TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-17 US claimed